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【雙語病例】A 54-year-old man with incidental CT finding

 Yudaxia 2015-11-03

Shown below are axial CT images through the kidneys. In order: unenhanced, arterial phase, and portal venous phase.


平掃:


動脈期:


門脈期:

1.Where is the salient abnormality located?

病變在哪里?

Liver

Pancreas

Kidney

Colon



MR axial images through the level of the kidneys are shown below in the following sequences:


T2WI FSE


T2WI FSE 脂肪抑制


T1WI 同相位(echo time = 4.6 msec)


T1WI 反相位 (echo time = 2.3 msec)


DWI


ADC圖


MR平掃


動脈期


門脈期:


平衡期

2.The right renal lesion restricts diffusion.

右腎病變彌散受限

True

False


3.There is invasion of the renal sinus fat.

病變侵犯腎竇脂肪

True

False


4.There is fat within the renal lesion.

病變內含有脂質成分

True

False


5.The renal lesion is T1 hyperintense to renal parenchyma.腎臟內病灶相對于腎實質呈T1WI高信號,。

True

False


6,,What is the most likely diagnosis?

Hyperdense cyst 高密度腎囊腫

Lymphoma 淋巴瘤

Angiomyolipoma 血管平滑肌脂肪瘤

Papillary renal cell carcinoma 乳頭狀腎癌

Clear cell renal cell carcinoma 透明細胞腎癌


選擇題答案:

  1. Kidney

  2. True

  3. False

  4. False

  5. False

  6. Papilary renal cell carcinoma


Findings
CT:


  • An exophytic hyperdense lesion is seen in the upper pole of the right kidney.

    右腎上極高密度結節(jié),突向腎外,。

  • Lesion demonstrates enhancement on arterial and portal venous phases.

    增強掃描動脈期及靜脈期可見病灶強化。

MRI:

  • An exophytic enhancing lesion is seen in the upper pole of the right kidney corresponding to hyperdense CT mass.

    與CT對應,,可見右腎上極腫塊,,向腎外生長,。

  • T1 and T2 hypointense relative to kidney.

    T1WI和T2WI上,病灶相對于腎臟呈略低信號,。

  • Restricts diffusion.

    彌散受限,。

  • No fat within the lesion, demonstrated on chemical shift imaging.

    病灶內無脂質成分,可見化學位移位移,。

  • No invasion of subjacent renal sinus fat.

    病灶沒有侵犯鄰近腎竇脂肪,。




Differential Diagnosis
  • Transitional cell carcinoma: Centrally located, poorly defined, peripherally dilated calyces.

    移行細胞癌:位置一般更靠近腎臟內部,邊界不清,,鄰近腎盞擴張,。

  • Angiomyolipoma: Detection of macroscopic fat.

    血管平滑肌脂肪瘤:病灶內可見脂肪成分

  • Oncocytoma: Cannot establish a definitive diagnosis and most require biopsy or surgery.

    嗜酸細胞瘤:單純通過影像很難確診,需要結合病理或手術明確診斷,。

  • Primary lymphoma: Usually large retroperitoneal mass than engulfs the kidney.

    原發(fā)性淋巴瘤:腹膜后腫塊,,通常體積較大,包繞腎臟,。

  • Secondary lymphoma: Hematogenous metastases to the kidneys in patients with known prior treated lymphoma. Multiple bilateral homogenous hypodense and hypoenhancing lesions are characteristic.

    繼發(fā)性淋巴瘤:其他部位淋巴瘤血行轉移至腎臟,。典型表現(xiàn)為雙腎多發(fā)均勻稍低密度病灶,增強后略強化,。




Diagnosis

Papillary renal cell carcinoma

乳頭狀腎細胞癌




Specific Subtypes of Renal cell carcinoma (RCC)
  • Clear cell: Most common subtype = 75% of renal cell carcinomas in most series

    腎透明細胞癌:最常見的類型,,約占腎細胞癌的75%。

  • Papillary: Second most common subtype

    乳頭狀腎細胞癌:第二常見亞型,。

  • Chromophobe 腎嫌色細胞癌

  • Collecting duct 腎集合管癌

  • Unclassified 未分類腎細胞癌




Imaging Findings for Specific Subtypes

    Clear cell RCC 腎透明細胞癌:

    • Tend to have greater enhancement and more heterogeneity.

      通常更加不均勻,,增強掃描強化更明顯

    • Termed clear cell by pathologists secondary to intracellular lipid and glycogen; the former can be detected by loss of signal intensity on opposed phase images when compared with corresponding in phase images.

      病理科醫(yī)師將細胞內脂質和糖原稱為透明細胞,病灶內的脂質成分可以通過MR同反相位上的信號衰減檢測出來,。

    Papillary cell RCC 乳頭狀腎細胞癌:

    • Enhances less than clear cell carcinoma.

      強化低于腎透明細胞癌

    • No lipid on chemical shift imaging.

      化學位移成像示病灶內沒有脂質成分

    • Restricts diffusion to a greater degree than clear cell carcinoma.

      相對于腎透明細胞癌,,彌散受限更明顯。

    • Lower T2-weighted signal intensity than clear cell renal carcinoma

      T2WI信號低于腎透明細胞癌,。

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